QUESTION 89. (Infective Mononucelosis)

A 16-year old boy presented with fever and a diffuse maculopapular rash. Examination revealed generalised cervical lymphadenopathy and hepatosplenomegaly. After intake of Ampicillin (prescribed by a local practitioner), the rash worsened. The most likely diagnosis is:

(a) Dengue fever
(b) Measles
(c) Drug-rash
(d) Infectious mononucleosis

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ANS- (d) Infectious mononucleosis

Patient of Infective mononucelosis treated with ampicillin develop an erythematous maculopapular eruption described as guttate psoriasis. Guttate psoriasis may be precipitated in almost all patients with infectious mononucleosis treated with amoxicillin. 

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