QUESTION 93. (Nitroglycerin)

Nitroglycerin is NOT used as an oral tablet because of its:

(a) Poor solubility
(b) Poor degradibility
(c) High pre systemic metabolism
(d) Unpalatabilty


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ANS- (c) High pre systemic metabolism

Nitroglycerin is available as sublingual tablet because of this route its directly absorb into systemic circulation else it will nearly 90% metabolised through liver & its affects wouldn’t show up.

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