Membrane receptors

  1. G Protein-Coupled Receptor (GPCR)
    Subtype Effect 2nd Messenger Action
    Gs Activates adenylate cyclase Stimulation of cAMP production Activates protein kinase A
    Gi Inhibits adenylate cyclase Inhibition of cAMP production
    Gq Activates phospholipase C Liberates DAG and IP3, mobilizing Activates protein kinase CCa2+
  2. Guanylyl Cyclase Receptor
    • Effector: Guanylyl cyclase
  3. Receptor Tyrosine Kinase
    • Effector: Tyrosine kinase
    • 2nd Messenger: Stimulation of cGMP
    • 2nd Messenger: MAP kinase
  4. Cytokine Receptor Tyrosine Kinase
    • Effector: JAK, tyrosine kinase
  5. Serine Kinase
    • Effector: Serine kinase
    • 2nd Messenger: STAT, MAP kinase
    • 2nd Messenger: Smads
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